Laguna’s practice includes decades-long activities as a curator, publisher, and organizer which have positioned her as a continued point of reference and inspiration in Buenos Aires. In 1999, the artist cofounded the legendary alternative space Belleza y Felicidad, which would later move to the outskirts of the city and host educational, artistic, activist, and poetry programs, expanding the community’s access to creativity and pleasure. Later, in 2017, she would open Comedor Gourmet (The Gourmet Soup-Kitchen) which redressed the soup kitchen model from food as necessity to a point of contact, identity, and happiness. Since the 2000s, under the pseudonym Dalia Rosetti, Laguna has published a series of novels, following feminist and queer storylines in styles reminiscent of adult and fan fiction.

Central to Laguna’s multifarious social projects in Buenos Aires is her singular artistic language, combining emotion, spontaneity, and innocence. Often incorporating found materials, from ribbons, glitter, shells, and studs, the artist’s paintings are dressed and decorated, reinforcing the work of art as stemming from the artist’s own sensibility. Laguna states, "I paint the paintings I want to have.” The works’ imagery negates any mistranslations of their conveyed meanings; a crying figure’s torrent of tears are emphasized by gold glitter so that their sadness is forefront. Laguna’s scale is invariably intimate, as she imagines the paintings’ movement and their transfer as tokens of affections.